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Barton, the discussant, took a cautionary view, saying that there are some things to consider before going out and telling patients to consider acetyl-carnitine for their peripheral neuropathy. It was unclear from the results reported whether the two treatment groups were well balanced and what criteria were used to define improvement for the secondary outcomes, she noted

When you get a head start, youre less likely to experience the big regain so common in the research

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You were promised a fix an end to the vicious cycle of symptoms

- Avoid in patients with severe hepatic impairment or conditions associated with tissue hypoxia

Neurology 1998